Phil Jones could return from a hamstring problem, while Jesse Lingard and Antonio Valencia are likely to play after being rested in midweek.
Marcus Rashford and Nemanja Matic are suspended for Manchester United, while Ander Herrera and Marcos Rojo are not yet considered fit enough to feature.
Diogo Dalot impressed on debut against Young Boys but his next start is set to come on Tuesday in the Carabao Cup. Wolves could name the same starting XI for a sixth consecutive league game.
Ivan Cavaleiro is expected to be their only absentee as he continues his recovery from a back injury.
MOTD COMMENTATOR’S NOTES
@Guymowbray: Young Boys weren’t a problem, but a meeting with an old boy might be for Jose Mourinho, with Wolves boss Nuno Espirito Santo having been his back-up goalkeeper for Porto from 2002 to 2004.
Three wins out of three in September has seen Manchester United return to ‘normal’ after August defeats brought early-season worry, and normally you’d expect them to comfortably see off a newly-promoted team at home.
Wolves, though, do not fit the newly-promoted norm. They’ve spent money, they have style and they play with no fear.
Nuno will bring his team to have a real go at Old Trafford, where Wolves last won in 1980. It should be a really good game.
VIEW FROM THE DUGOUT
Manchester United manager Jose Mourinho, asked about the influence of his agent, Jorge Mendes, at Wolves: “I think the work in Wolves is good because it’s not just about the Portuguese influence – Portuguese manager, staff and players – it is also about getting the right ones and I think they have got good young players and they have also got good, experienced, stable players.
“So, they got this season, the Portuguese national team goalkeeper [Rui Patricio], they got [Joao] Moutinho, who is one of the players of the 100 caps club.
“The young ones are young boys with good potential and you can see the work of the coaching staff – and the team is a really, really good team.”
Wolves head coach Nuno Espirito Santo: “Jose Mourinho was my manager for two years – what we achieved for Porto will be in our memories forever.
“To all the players that were in the squad – he was a big inspiration. But then things change, you go on with your career personally – he was a big inspiration.”
All sorts of questions were being asked about Manchester United when they lost to Tottenham at the end of August, but since then they have won three out of three, all away from home.
United have got some momentum now and their troubles seem a long time ago. I can only see a home win.