Four trucks are on fire near the town of Sheepmoor in Mpumalanga.
The N2 is closed between Ermelo and Piet Retief, and is expected to remain so for most of Wednesday.
This brings the number of trucks torched over the past few days to 20.
SAPS leadership is due to address the media on the attacks.
The torchings have so far been reported in KwaZulu-Natal, Mpumalanga, and Limpopo.
The briefing will be attended by police commissioners from affected provinces.
They will provide information on police efforts to end the attacks and how they plan to catch the perpetrators.
Source: eNCA
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